Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.700 None 0.983 2577 53 1997 2020
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2 		Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.500 None 0.983 987 35 2002 2020
Entrez Id: 65018
Gene Symbol: PINK1
PINK1 		Q9BXM7 PTEN induced kinase 1 Kinase 209 0.516 0.769 1.9E-10 0.600 None 0.987 376 12 2002 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.600 None 0.974 304 20 1998 2020
Entrez Id: 2629
Gene Symbol: GBA
GBA 		P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.500 None 0.989 264 15 2004 2020
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3 		Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.400 None 0.935 185 7 1994 2020
Entrez Id: 7054
Gene Symbol: TH
TH 		P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.600 None 0.979 141 3 1989 2020
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.400 None 0.983 117 0 1993 2020
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		Q99497 Parkinsonism associated deglycase Enzyme 161 0.535 0.808 0.75 0.600 None 0.973 110 8 2003 2020
Entrez Id: 4129
Gene Symbol: MAOB
MAOB 		P27338 monoamine oxidase B 152 0.533 0.808 1.00 0.600 None 0.991 110 1 1993 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.400 None 0.906 96 6 1995 2020
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.200 None 0.922 90 1 1994 2020
Entrez Id: 6620
Gene Symbol: SNCB
SNCB 		Q16143 synuclein beta Transporter 60 0.619 0.577 6.8E-02 0.100 None 0.966 89 2 1999 2020
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.100 None 0.953 85 6 1984 2020
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1 		P09936 ubiquitin C-terminal hydrolase L1 Enzyme 260 0.482 0.885 0.99 0.100 None 0.948 77 4 1999 2020
Entrez Id: 6623
Gene Symbol: SNCG
SNCG 		O76070 synuclein gamma Transporter 122 0.550 0.615 8.5E-04 0.100 None 0.959 74 1 1999 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.100 None 0.983 59 6 2006 2020
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.600 None 0.931 58 3 1995 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.980 50 0 1999 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 0.977 43 0 2006 2020
Entrez Id: 1917
Gene Symbol: EEF1A2
EEF1A2 		Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 166 0.554 0.808 1.00 0.100 None 0.974 39 0 2004 2020
Entrez Id: 1121
Gene Symbol: CHM
CHM 		P24386 CHM Rab escort protein Enzyme 82 0.592 0.654 1.00 0.100 None 0.892 37 1 2000 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.400 None 0.971 35 3 1993 2020
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.100 None 0.970 33 0 2016 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.300 None 0.875 32 2 2002 2020